Isotopically Labeled Compounds
Medchemexpress LLC Venlafaxine-d6 hydrochloride | 1062606-12-5 | 98.2% | 25 MG
Venlafaxine-d6 (hydrochloride) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine hydrochloride is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor and an antidepressant. It is intended for research use only. Deuteration has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories METHANOL-D4 (D, 99.8%), 10 ML, 811-98-3
METHANOL-D4 (D, 99.8%), 10 ML, 811-98-3
Cambridge Isotope Laboratories ACETONITRILE (2-13C, 99%), 1 G, 1722-09-4
ACETONITRILE (2-13C, 99%), 1 G, 1722-09-4
Cambridge Isotope Laboratories Dimethyl Sulfoxide-D6 (D, 99.9%), 5 X 1 G, 2206-27-1
Dimethyl Sulfoxide-D6 (D, 99.9%), 5 X 1 G, 2206-27-1
Sigma Aldrich Fine Chemicals Biosciences Chloroform-d 99.8 atom % D, contains 0.03 % (v/v) TMS | 865-49-6 | MFCD00000827 | 100G
Chloroform-d 99.8 atom % D, contains 0.03 % (v/v) TMS | Purity: >=99% (CP) | Mol Wt: 120.38 | 865-49-6 | MFCD00000827 | 100G
Cambridge Isotope Laboratories NITROMETHANE (13C, 99%), 0.5 G, 32480-00-5
NITROMETHANE (13C, 99%), 0.5 G, 32480-00-5
Medchemexpress LLC DM4-d6 | 99.1% | 786.40 | 1 MG
DM4-d6 is deuterium labeled DM4, an antitubulin agent that inhibits cell division and can be used in the preparation of antibody agent conjugate.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories Tetrahydrofuran-D8 (D 99 5%) 10 x 0 5mL
Tetrahydrofuran-D8 (D 99 5%) 10 x 0 5mL
Medchemexpress LLC Rel-Ritonavir-d6 | 1217720-20-1 | 98.7% | C37H42D6N6O5S2 | 500 UG
rel-Ritonavir-d6 is the deuterium labeled rel-Ritonavir, a stable isotope of Ritonavir. Ritonavir is an inhibitor of HIV protease, commonly used in the study of HIV infection and AIDS, and also functions as a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM. The incorporation of stable heavy isotopes into drug molecules, such as deuterium in rel-Ritonavir-d6, is largely for quantitation during the drug development process and has shown potential to influence pharmacokinetic and metabolic profiles.
- Deuterium labeled rel-Ritonavir
- Inhibitor of HIV protease
- Used to study HIV infection and AIDS
- SARS-CoV 3CLpro inhibitor
- Functions as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical Prostaglandin D2 methyl ester, Purity: ≥97%, CAS: 49852-81-5, 1 mg
PGD2 methyl ester is a more lipid-soluble, cell-permeable prodrug form of PGD2.{14117} It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.{11494}
Cambridge Isotope Laboratories Chloroform-D ''''''''100%'''''''' (D, 99.96%), 10 X 0.5Ml, 865-49-6
Chloroform-D ''''100%'''' (D, 99.96%), 10 X 0.5Ml, 865-49-6
Medchemexpress LLC Calcitriol-d6 | 78782-99-7 | 99.3% | C27H38D6O3 | 5 MG
Calcitriol-d6 is the deuterium labeled form of Calcitriol, which is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR). It is the hormonally active form of vitamin D. This compound can serve as a valuable tool in quantitative analysis.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Internal standard for quantitative analysis of Calcitriol in plasma.
Sigma Aldrich Fine Chemicals Biosciences N,N-Dimethylformamide-d7 >=99.5 atom % D | 4472-41-7 | MFCD00003286 | 1G
N,N-Dimethylformamide-d7 >=99.5 atom % D | Purity: >=99% (CP) | Mol Wt: 80.14 | 4472-41-7 | MFCD00003286 | 1G
Sigma Aldrich Fine Chemicals Biosciences Toluene-d8 99.6 atom D10G
Toluene-d8 is a deuterated NMR solvent useful in NMR-based research and analyses. Spin-lattice relaxation time (T 1) viscosity and density have been measured over -35 to 200C range. The temperature dependent chemical shifts in the proton NMR spectra of -unsaturated ketones in toluene-d8 has been studied.
Sigma Aldrich Fine Chemicals Biosciences Acetone-d6 99.9 atom D
Acetone-d6 (CD3COCD3 Hexadeuteroacetone) is the hexadeuterated form of acetone in which all hydrogen atoms in acetone molecule have been replaced by deuterium (D) atoms. It is a standard purity solvent for NMR (Nuclear Magnetic Resonance) analyses. Absorption spectra of CD3COCD3 samples cooled in molecular jet (jet-cooled) have been evaluated in the range of 51000-54000cm-1. Collision of its molecular ions with a perdeuterated surface (C20D41 SAu) was investigated by ion-surface collision spectroscopy. The Infrared and Raman spectra of acetone-d6 have been analyzed. It undergoes H-2H exchange reaction with acetone d0 to afford acetone d1 and d5.