Isotopically Labeled Compounds
Medchemexpress LLC Tamoxifen-d3 hydrochloride | 54965-24-1 | 99.0% | 410.99 | 1 MG
Tamoxifen-d3 hydrochloride is a deuterated labeled Tamoxifen that functions as an orally active, selective estrogen receptor modulator (SERM). It blocks estrogen action in breast cells and activates estrogen activity in other cells, such as bone, liver, and uterine cells. This compound is also a potent Hsp90 activator, enhancing its molecular chaperone ATPase activity. It potently inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 values of 0.1 μM and 1.8 μM, respectively. It activates autophagy and induces apoptosis, and can induce gene knockout of CreER(T2) transgenic mouse.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Nonanoic acid-d2 | 62689-94-5 | 100 MG
Nonanoic acid-d2 is a deuterium-labeled, naturally occurring saturated fatty acid with nine carbon atoms. It reduces bacterial translocation, enhances antibacterial activity, and increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2. This compound serves as a tracer or internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS. Deuterium incorporation in drug molecules allows for tracer applications in drug development, potentially influencing pharmacokinetic and metabolic profiles.
- Deuterium-labeled nonanoic acid
- Reduces bacterial translocation
- Enhances antibacterial activity
- Increases secretion of porcine β-defensins 1 (pBD-1) and pBD-2
- Functions as a tracer in drug development
- Serves as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- May affect pharmacokinetic and metabolic profiles of drugs
Cambridge Isotope Laboratories 3-EPI-25-HYDROXYVITAMIN D3 UNLABELED 50 UG/ML IN ETHANOL, 1 ML
3-EPI-25-HYDROXYVITAMIN D3 UNLABELED 50 UG/ML IN ETHANOL, 1 ML
Cambridge Isotope Laboratories METHANE (12C, 99.95%; D4, 98%), 1 L, 558-20-3
METHANE (12C, 99.95%; D4, 98%), 1 L, 558-20-3
Medchemexpress LLC Triptolide-d3 | 38748-32-2 | MFCD00210565 | 91.9% | 363.42 g·mol⁻¹ | C20H21D3O6 | 1 MG
Triptolide-d3 (d3) is the deuterium-labeled isotopologue of triptolide supplied as a stable isotope standard for analytical and research applications. It is intended for use as an internal standard or tracer in mass spectrometry and isotopic studies, and is provided in a 1 mg package.
- Deuterium-labeled (d3) isotopologue for internal standard use in mass spectrometry
- Purity 91.9% (>90%)
- Molecular formula C20H21D3O6
- Molecular weight 363.42 g·mol⁻¹
- Package size 1 mg
- Store at -20°C; protect from light; handle under inert atmosphere where indicated
Sigma Aldrich Fine Chemicals Biosciences Cyclohexanone-d10 98 atom % D | 51209-49-5 | MFCD00144023 | 5G
Cyclohexanone-d10 98 atom % D | Purity: 99% (CP) | Mol Wt: 108.2 | 51209-49-5 | MFCD00144023 | 5G
Cambridge Isotope Laboratories VITAMIN D2 (ERGOCALCIFEROL) UNLABELED 100 UG/ML IN ETHANOL, 1 ML
VITAMIN D2 (ERGOCALCIFEROL) UNLABELED 100 UG/ML IN ETHANOL, 1 ML
Medchemexpress LLC 1,2-dibromoethane-d4 | 22581-63-1 | MFCD00037499 | 99.0% | 191.89 g/mol | C2D4Br2 | 1 G
1,2-dibromoethane-d4 is the deuterium-labeled (d4) isotopologue of 1,2-dibromoethane used as an analytical standard and solvent in research and spectroscopic applications. It provides high isotopic enrichment and chemical purity suitable for NMR, tracer, and synthesis work.
- Deuterium-labeled (d4) isotopologue of 1,2-dibromoethane.
- Isotopic purity ~99 atom % D.
- Assay purity 99.0%.
- Molecular formula C2D4Br2; molecular weight 191.89 g/mol.
- Liquid at ambient temperature; supplied in 1 G packages.
- Intended for research and analytical applications.
Sigma Aldrich Fine Chemicals Biosciences L-Glutamine-13C5 98 atom % 13C, 95% (CP) | 184161-19-1 | MFCD00144603 | 100MG
L-Glutamine-13C5 98 atom % 13C, 95% (CP) | Purity: 95% (CP) | Mol Wt: 151.11 | 184161-19-1 | MFCD00144603 | 100MG
Medchemexpress LLC Sodium formate-13C,d1 | 1215684-17-5 | 98.0% | 71.01 g/mol | 13CHDNaO2 | 25 MG
Sodium formate-13C,d1 is a stable-isotope labeled form of sodium formate in which the formyl carbon is 13C-labeled and the hydrogen is deuterated (d1). It is supplied as a solid reagent for use as an isotopic tracer and as a reducing reagent in biochemical and catalytic studies, and for material synthesis.
- Stable-isotope labeled: 13C and d1
- Purity: 98.0%
- Molecular weight: 71.01 g/mol
- Chemical formula: 13CHDNaO2
- CAS number: 1215684-17-5
- Available pack sizes: 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg
Medchemexpress LLC Adenine-13C | 86967-48-8 | 99.1% | 136.12 g/mol | C5H5N5 (13C-labeled) | 10 MG
Adenine-13C is a stable isotope-labeled adenine (single 13C) supplied as a white to off-white solid for use in mass spectrometry, metabolic tracing, and biochemical assays as an internal standard or tracer. It is intended for research use and should be stored protected from light under inert atmosphere.
- Stable isotope-labeled adenine with a single 13C atom.
- High purity suitable for analytical applications and tracer studies.
- White to off-white solid, easy to weigh and handle.
- Recommended storage: protected from light, under nitrogen, refrigerated or frozen for long-term stability.
- Applications: mass spectrometry internal standard, metabolic flux analysis, and biochemical research.
Medchemexpress LLC Spermine-d20 | 71-44-3 | 98.5% | 222.46 g/mol | C10H6D20N4 | 25 MG
Spermine-d20 is a deuterium-labeled isotopologue of the polyamine spermine supplied as a research-grade stable isotope standard for analytical and biological studies. It is intended for use as an internal standard, tracer, or reference material in mass spectrometry and metabolomics. For research use only.
- Deuterium-labeled standard for isotope dilution and tracer studies.
- High purity suitable for analytical applications.
- Used as an internal standard in LC-MS/MS and GC-MS workflows.
- Supplied as a small quantity solid to minimize waste for method development.
- Intended for research use only; not for human or clinical applications.
Medchemexpress LLC Benzoic-2,3,5,6-d4 acid, 4-hydroxy-, propyl ester | 1219802-67-1 | 184.23 | 5 MG
Propylparaben-d4 is the deuterium-labeled version of Propylparaben, an antimicrobial preservative naturally produced by plants and bacteria. It is commonly used in cosmetics, pharmaceuticals, and foods. Propylparaben has been shown to disrupt antral follicle growth and steroidogenic function by altering cell-cycle, apoptosis, and steroidogenesis pathways, and also decreases sperm number and motile activity in rats.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Ethylmalonic acid-d5 | 66311-22-6 | 98.09% | 137.15 | 5 MG
Ethylmalonic acid-d5 | 66311-22-6 | 98.09% | 137.15 | 5 MG
Sigma Aldrich Fine Chemicals Biosciences L-Serine-13C3,15N 98 atom % 13C, 98 atom % 15N, 95% (CP) | 202407-34-9 | MFCD00144678 | 100MG
L-Serine-13C3,15N 98 atom % 13C, 98 atom % 15N, 95% (CP) | Purity: 95% (CP) | Mol Wt: 109.06 | 202407-34-9 | MFCD00144678 | 100MG